Doctors on Glutathione

We Cannot Live Without Glutathione

"Glutathione is a substance, the levels of which in our cells are predictive of how long we will live. There are very few other factors which are as predictive of our life expectancy as is our level of cellular glutathione. We literally cannot survive without this antioxidant." - Earl Mindell, R. Ph., Ph.D.

"No other antioxidant is as important to overall health as glutathione. It is the regulator and regenerator of immune cells and the most valuable detoxifying agent in the human body. Low levels are associated with hepatic dysfunction, immune dysfunction, cardiac disease, premature aging, and death." - The Immune System Cure, Lorna R. Vanderhaeghe and Patrick J.D. Bouic, Ph.D.

"Without glutathione, other important antioxidants such as vitamins C and E cannot do their job adequately to protect your body against disease." - Breakthrough in Cell Defense, Allan Somersall, Ph.D., M.D., and Gustavo Bounous, M.D. FRCS(C). Glutathione is a tri-peptide of the amino acids cysteine, glycine, and glutamic acid. 

A deficiency of glutathione can cause hemolysis (destruction of red blood cells, leading to anemia) and oxidative stress. - [PDR Medical Dictionary. Spraycar. 1999]

"Without glutathione, other important antioxidants such as vitamins C and E cannot do their job adequately to protect your body against disease." - Breakthrough in Cell Defense, Allan Somersall, Ph.D., M.D., and Gustavo Bounous, M.D. FRCS(C).

Dr. Lombard points out in his book, "The Brain Wellness Plan," that Glutathione is one of the most powerful antioxidants in the body. Depressed glutathione levels are associated with the increased generation of free radicals found in Parkinson’s patients, for example, and contributes to further brain cell death." - Excerpts from the Willner Window Radio Show: Program aired on 5-3-98

Learn more about increasing your Glutathione levels in your body: http://www.maxhealthforlife.com

Comments about Glutathione from Doctors

Glutathione is Vital to your Health

As we age, there is a precipitous drop in Glutathione levels. Lower Glutathione levels have been implicated in many diseases associated with aging. Journal of Clinical Epidemiology 47: 1021-28 1994 Antioxidants are well documented to play vital roles in health maintenance and disease prevention. Glutathione is your cells' own major antioxidant. Biochemical Pharmacology 47: 2113-2123 1994

Glutathione plays a role in eliminating many carcinogens as well as maintaining immune function. Cancer Letters 57: 91-94 1991

Strong muscular activity, such as that experienced by athletes, generates oxy-radicals (free radicals) leading to muscle fatigue and poorer performance. Glutathione neutralizes these radicals. Sport Medicine 21: 213-238, 1996

In the annual Review of Biochemistry 52: 711-780 1983 Lester Packer, Ph.D., writes that maintaining high levels of Glutathione is critical for life and that low glutathione levels are a marker for death at an early age. Glutathione diminishes as we age.

Glutathione detoxifies many pollutants, carcinogens, and poisons, including many in fuel exhaust and cigarette smoke. It retards damage from radiation such as seen with loss of the ozone.

Researchers have found that people over the age of 60 who have high blood levels of Glutathione have fewer illnesses, lower cholesterol and blood pressure and healthier weights than people with lower levels.

People over 69 with low blood levels of Glutathione are more likely to have diabetes, arthritis and heart disease. Glutathione truly is an amazing anti-oxidant, immune booster and detoxifier.

Get more information: http://www.maxhealthforlife.com

Glutathione and ADHD Children

The effect of low Glutathione levels in children suffering from attention deficit hyperactivity disorder (ADHD).

Redox Rep. 2006;11(4):163-72. Department of Medical Chemistry, Biochemistry and Clinical Biochemistry, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic.

Attention deficit hyperactivity disorder (ADHD) belongs to the neurodevelopmental disorders characterized by impulsivity, distractibility and hyperactivity. In the pathogenesis of ADHD genetic and non-genetic factors play an important role. It is assumed that one of non-genetic factors could be oxidative stress.

This randomized, double-blind, placebo-controlled study investigated the influence of intercellular reduced Glutathione and oxidized Glutathione in children suffering from ADHD and total antioxidant status (TAS). This is the first investigation of the redox Glutathione state in relation to ADHD.

RESULTS: One month of Glutathione administration caused a significant decrease in oxidized Glutathione and a highly significant increase in Glutathione levels as well as improvement of Glutathione/oxidized Glutathione ratio in comparison to a group of patients taking a placebo. TAS in children with ADHD was decreased in comparison with reference values. Glutathione administration normalized the TAS of ADHD children in this study.

For more information about Glutathione: http://maxhealthproducts.net/

Glutathione and Vision

Aging individuals encounter higher rates of cataract, glaucoma, and macular degeneration. Diabetics are at particularly high risk for cataract. The high blood sugar levels found in diabetics have a direct effect on lens health and elevating oxidative stress.

One the most feared concerns in the elderly is going blind or having a major loss of vision. Scientific studies conclusively show that degenerative eye disease is not inevitable.

The concentration of Glutathione in the lens of the eye is higher than in most other tissues. Glutathione protects the structural proteins and enzymes necessary for the maintenance of lens flexibility and clarity against free radical assault.

Aging lenses of the eye lose Glutathione, and this reduction of Glutathione has been found to lead directly to reactions that cause deterioration of the lens.

For more details: http://MaxHealthforLife.com

What Doctors Are Saying About Glutathione

“Glutathione is the unsung antioxidant…the one that makes all the others work.” Robert Atkins MD, founder of the Atkins Center for Complementary Medicine.

"No other antioxidant is as important to overall health as Glutathione. It is the regulator and regenerator of immune cells and the most valuable detoxifying agent in the human body.

Low levels are associated with hepatic dysfunction, immune dysfunction, cardiac disease, premature aging, and death." Lorna R. Vanderhaeghe & Patrick J.D. Bouic, Ph.D. The Immune System Cure.

"Glutathione is a substance, the levels of which in our cells are predictive of how long we will live.

There are very few other factors which are as predictive of our life expectancy as is our level of cellular Glutathione.”

Glutathione has been called the "Master Antioxidant", and regulates the actions of lesser antioxidants such as vitamin C, and vitamin E within the body. "We literally cannot survive without this antioxidant." Earl Mindell, R.Ph., Ph.D, in What You Should Know about the Super Antioxidant Miracle.

One reason why it is so important to maintain high levels of Glutathione is that it is crucial for the detoxification of carcinogens. Most people do not inherit "cancer genes"; rather, they have a genetic weakness in their detoxification system. Glutathione is an extremely important part of the detoxification system, and thus of our defenses against cancer.

Glutathione may also be one of the most important keys to longevity. Centenarians have been found to have higher levels of Glutathione than would be expected for their age. “Boosting one's Glutathione levels ...should be one of the first items on anyone's anti-aging agenda.” - Ivy Greenwell in The Antioxidant Network, A brief review of "The Antioxidant Miracle," by Lester Packer, PhD and Carol Colman.

"Without Glutathione, other important antioxidants such as vitamins C and E cannot do their job adequately to protect your body against disease." Allan Somersall, Ph.D., M.D., and Gustavo Bounous, M.D. FRCS(C) in Breakthrough in Cell Defense.

"If there is one survival tool every HIV+ person should consider, it is taking dietary supplements that increase Glutathione production." - Michael Mooney, Author of Built to Survive: A Comprehensive Guide to the Medical Use of Anabolic Steroids, Nutrition and Exercise for HIV+ men and women.

Dr. Lombard points out in his book, "The Brain Wellness Plan"...the brain’s high fat content renders it especially vulnerable to free radicals, so that the body has defined specific ways to protect brain cell fatty acids through special antioxidants.... Glutathione is one of the most powerful antioxidants in the body. Depressed Glutathione levels are associated with the increased generation of free radicals found in Parkinson’s patients that contributes to brain cell death."

Parkinson's occurs in about one of every hundred people over the age of 65. It is a slow progressing disease of the nervous system that results in progressive destruction of brain cells (neurons) in an area of the brain. Death can occur as a result of secondary complications such as infections.

Several factors explain why Glutathione is so beneficial in Parkinson’s disease. 1) Glutathione increases the sensitivity of the brain to dopamine. Although Glutathione doesn't raise dopamine levels, it allows the dopamine in the brain to be more effective. 2) Glutathione's powerful antioxidant activity protects the brain from free radical damage. 3) An even more intriguing benefit of Glutathione lies in its powerful detoxification ability.

Need more information about Glutathione and how it prevents diseases and age related illnesses? As of May 2006 about 70,736 medical articles and research documents on Glutathione were posted on the PubMed website. PubMed is hosted by the USA government as a resource for researchers and medical doctors. This site encompasses the libraries of “National Center for Biotechnology Information (NCBI), National Library of Medicine (NLM), and the National Institute of Health (NIH).
PubMed: http://www.ncbi.nlm.nih.gov/pubmed

For more information click: http://MaxHealthforLife.Com

Glutathione: Be Healthier and Live Longer

From an article by Ward Dean MD in Vitamin Research News.

Mitochondrial Glutathione is critical to the healthy cell, and is probably the most important antioxidant defense system within the mitochondria cell. Age-related alterations in these enzymes can have a profound adverse effect on health and longevity.

Age-Related Changes in Glutathione

Drs. J.P. Richie and Calvin Lang of the Department of Biochemistry, University of Louisville, were the first to propose that a Glutathione deficiency might be a biochemical cause of the aging process. They demonstrated that Glutathione blood levels predictably declined with age in healthy men and women ranging in age from 20 to 94.

Scientists at the University of Pavia found that Glutathione levels continue to decline with age. Subjects with the highest Glutathione levels survived the longest.

In another study of enzyme activity in the very old, Dr. Helle Anderson and colleagues at Odense University in Denmark compared the levels of Glutathione in 41 centenarians between 100-105 years old to that in 52 community controls between the ages of 60-79. They found that the mean Glutathione activity was significantly higher in centenarians than in the group of younger elderly subjects, and that centenarians with the best functional capacity tended to have the highest Glutathione levels.

Dr. Lang’s group evaluated Glutathione levels in 87 women in excellent physical and mental health, ranging in age from 60 to 103. The scientists found that all subjects had very high blood Glutathione levels. They followed these women for five years and concluded that “high blood Glutathione concentrations … are characteristic of long-lived women.”

Glutathione in Health and Disease

Just as high Glutathione levels are related to increased survival and longer life in all organisms tested so far, lower levels are related to poorer health and a number of chronic degenerative diseases, including heart disease, arthritis, hypertension, diabetes, cancer, genitourinary, gastrointestinal, and musculoskeletal diseases, age-related macular degeneration (ARMD), preeclampsia, cataracts, chronic renal failure, leukemia, respiratory diseases such as COPD and adult respiratory distress syndrome (ARDS), hearing loss, and AIDS.

Dr. Lang concluded that decreased Glutathione levels are risk factors for chronic diseases and may be used to monitor the severity and progress of the diseases.

Conversely, Dr. Mara Julius of the Department of Epidemiology, University of Michigan, in a study of 33 subjects over the age of 60, found that higher Glutathione levels were associated with fewer illnesses and higher levels of self rated health, lower cholesterol, lower body mass index and lower blood pressures. The author noted that this was the first study that showed an association of higher Glutathione levels with higher levels of physical health in a community-based sample.

Glutathione and Detoxification

One of Glutathione’s primary roles in the body is to detoxify a number of drugs and toxins. Acetaminophen (APAP, i.e.,Tylenol) has been studied intensively in regard to its Glutathione-depleting properties, and with regard to Glutathione’s ability to prevent APAP-induced liver and kidney damage. Since GSH Glutathione levels decrease with aging in all tissues, including the liver and kidney, older organisms are thus at even greater risk to APAP-induced liver and renal damage than younger organisms.

Increasing Tissue Glutathione Levels

It is clear that those with the highest Glutathione levels are likely to live the longest in the best of health.

Read this article in its entirety refer to “Vitamin Research News Vol. 20, Number 8 by Ward Dean, MD”.

The product that has been documented to produce high levels of Glutathione concentrations in the body is MaxGXL. http://MaxHealthProducts.Net/order.htm

Free 20-page eBook available "Glutathione Master Antioxidant" http://MaxHealthProducts.Net/ebook.htm